Several satellite screens showed images of the Muslim Brotherhood march on the May Fifteen Bridge, west of Cairo, shooting gunfire, on Friday afternoon.
The violence started as Egypt braces for a nationwide protest on Friday, dubbed "the Friday of Wrath" by the Muslim Brotherhood, two days following the forcible dispersal of their sit-ins by the army and the police.
Marches headed to Ramses Square have already started moving from Omraneya, Mourad Steeet and Istiqama Mosque. Mada Masr witnessed clahses between protesters in residents in the nearby area of Azbakiya.
Borrowing a name from the 28 January "Friday of Wrath" that led to former President Hosni Mubarak's ouster in 2011, today's protests are expected to turn violent. They follow two days of scattered violence around Egypt, as Brotherhood supporters clashed with police and residents in various locations.
The Brotherhood had announced that the day will be marked by twenty-eight marches starting from several mosques in Cairo, according to the National Coalition for the Support of Legitimacy.
"Despite our pain for the loss of martyrs and the suffering of the injured, the crimes of the coup regime have made us more determined to reject it," the coalition said in a statement on Friday. The coalition also vowed that the protests will remain peaceful.
In an address to his followers on Friday, Brotherhood Supreme Guide Mohamed Badie said that protests will not stop because the Egyptian people want freedom. He added that the military's ouster of President Mohamed Morsi, who belonged to the group, is part of its plan to take over and rule Egypt.
Meanwhile, the army deployed tanks around Tahrir Square, blocking all entrances, ahead of the Brotherhood's planned protests.
According to the latest death toll announced by the Ministry of Health on Thursday, 638 people were killed during Wednesday's violence.
[This article originally appeared on Mada Masr.]